Autopsy, derived from the Greek ‘autos’ and ‘opsomeri’ means ‘to see for oneself, and originates from mummification using human dissection around 3000BC. Over five millennia it has enabled the study of human anatomy, physiology, and pathophysiology culminating in 21st century medicine.
After such a rich and rewarding history, autopsy is on the brink of extinction. During the 1980s, around 30% of adult inpatient deaths in the United Kingdom were followed with consented autopsy, yet by 2013 this figure had fallen to less than 1% . The severity of this decline has led to the extinction of consented autopsy in 25% of hospitals in the UK. Marked declines have been noted around the globe. Read More>>>>>>>>
Pituitary inflammatory lesions are uncommon: a granulomatous inflammatory reaction can be caused by systemic tuberculosis, syphilis or fungal infections, being usually an incidental autopsy finding.
They come to the pathologist more frequently when they are at an advanced stage, producing a mass effect and/or hypothalamic. However, the most enigmatic form of granulomatous hypophysitis is idiopathic. Exceptional is the association of this inflammatory lesion with adenomatous neoplastic one. The aim of our report was to make assumptions on the pathogenesis of this unlikely association. Read More>>>>>>
Post Monitor Studies for the Treatment of Speech Hand Synchronization for Adult who Stutter: 3 Months Follow Up
The aim of the above study was to follow up for 3 months of stuttering therapy procedure in adults who stutters accomplishing spontaneous fluent speech. In this pilot study, 30 subjects were selected and divided into (i) speech-hand synchronization (SHS) (ii) Camperdown Programme (CP) and (iii) control group (CG) for the treatment therapy.
The post-treatment sessions were carried out for 3 months for 50 minutes a day for 10 weeks and each week was considered as week days (5 days). The SHS and CP patients could not show the significant association in post-treatment sessions for 3 months’ sessions. SSI-4, OASES and LCB were seems to be non-significant. However, SHS and CP was also seeming to be positive effect in assessments measuring well-being. Read More>>>>>>>
Metastatic Salivary Duct Carcinoma of the Submandibular Gland Presenting as a Poorly Differentiated Carcinoma of Unknown Primary
In this research note, Rosemarie Di Donato and his team describe Salivary duct carcinoma is an aggressive malignancy that most commonly arises in the parotid gland.
Few case reports describe this entity occurring in the submandibular gland. This entity can metastasize locally early and therefore is an important differential diagnosis of metastatic disease in cervical lymph nodes. Read More>>>>>>>
The Pap test has been the most successful screening method for the prevention of cervical cancer with a seventy per cent decrease in its death rate since 1950. This is in the face of the sexual revolution of the 1960’s occasioned in part by the introduction of the birth control pill in 1960.
The subsequent change in sexual mores and increased promiscuity should have resulted in an increased incidence and death rate from cervical cancer. In fact the detection of cervical intraepithelial neoplasia (CIN) increased dramatically and its subdequent treatment resulted in successful cancer prevention. Read More>>>>
Morphological Aspect of Oral Lichen Planus Lesions Depending on Infection with Hepatitis C Virus and Functional Hepatic Tests
To determine the frequency of association of oral lichen planus with HCV infection and to establish a correlation between the severity of hepatic involvement and that of lichen planus lesions. Included 80 patients with oral lichen planus. All patients included in the study underwent biochemical liver function tests.
Statistical analysis of clinical and para-clinical parameters was performed. The group of HCV-positive patients with oral lichen planus represented 42.5% of the study group. It was found that oral lichen planus with reticular lesions was the predominant clinical form. Regarding the relationship between the severity of oral lichen planus lesions and that of hepatic involvement, no correlation could be established between the degree of alteration of liver function tests and the severity of oral lesions. Read More>>>>>>>>>>>
Primary bone tumors are commonly encountered in cats and dogs. The proportions of benign and malignant neoplasms of bones are approximately equal. In cats Osteosarcomas may be of central or medullary and peripheral (periosteal and parosteal=juxtacortical) origin.
Sarcomas arising within bones are more common and consistently more malignant than sarcomas of periosteal origin. Parosteal osteosarcomas are included in the peripheral (surface) malignant tumors of bones with their well-differentiated osteosarcomatous features. Besides, invasion of the underlying cortex which is a commonplace and a contrasting feature in distinguishing periosteal osteosarcoma of other peripheral malignant tumor of the bones from parosteal osteosarcoma. Read More>>>>>>>>>