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Palatal rugae a finger print of oral cavity

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The term “forensic” is derived from Latin, meaning forum or a place where legal matters are discussed. The science of dentistry as related to the law is known as Forensic dentistry or Forensic odontology. Identification of unknown human bodies is essential in modern societies for legal and humanitarian reasons.

Pattern of palatal rugae
Pattern of palatal rugae

Forensic science also is not local, but global—we are all working in concert to address criminal justice issues, terrorism, health issues, and public safety. Forensic dentistry mainly involves the identification of an assailant by comparing a record of their dentition with a record of a bite mark left on a victim.  Read More>>>>>>>

Omitting Manual Errors with Ready-To-Use Syringes

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Administration of wrong medication due to manual errors is a mistake that is unpredictable and the results of which are imperceptible.

Syringe
Syringe

Application of ready-to-use syringes and automating the whole process can help in omitting these manual errors and ensure the safety of the patients. However, the extant model of development and implementation of such automated systems are costly and out of the reach of most hospital settings. It is evident that the method is of no use till a cost efficient model of the same is developed. Read More>>>>>>

Pneumatosis Intestinalis in Patient with Relapsing Polychondritis

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Relapsing polychondritis (RP) involves recurrently and progressively proteoglycan-rich organs and was first described in 1923 as “Polychondropathia. Yun et al. reported first RP case in Korea. Meanwhile, pneumatosis intestinalis (PI) refers to the presence of gas within the submucosa or subserosa of the bowel well.

Chest plain radiography
Chest plain radiography

In 2007, a RP patient who presented PI was reported in Korea for the first time in the world. We have then experienced a second PI case in a patient with RP. We suspected an association between RP, the episode of PI, and possibly steroid use as well. We examined the case of pneumatosis intestinalis in a 44-year-old male of RP patient. Read More>>>>>>>

Multiple Modes of Blood Coagulation

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The standard view of blood coagulation is based on the idea that a “cascade” of enzymatic events, the “intrinsic” and “extrinsic” pathways of coagulation both generating thrombin, which converts fibrinogen into an insoluble fibrin clot.

Classic coagulation cascade
Classic coagulation cascade

Consequently, much of the biomedical focus relating to blood coagulation has been on the clotting factor thrombin (clotting factor IIa), resulting from the “trypsinic” cleavage of prothrombin (clotting factor II) into thrombin (clotting factor IIa). For example, citrate is added to donated blood units to chelate Ca(II), which prevents the activation of carboxylated pro-factors (clotting factors II,VII, IX, X) into enzymatically functioning proteins (factors IIa, VIIa, IXa, Xa respectively). Read More>>>>>>>

A Granulomatous Hypophysitis “Consequent” to a Silent ACTH Cell Adenoma

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Pituitary inflammatory lesions are uncommon: a granulomatous inflammatory reaction can be caused by systemic tuberculosis, syphilis or fungal infections, being usually an incidental autopsy finding.

Periphery of the adenoma
Periphery of the adenoma

They come to the pathologist more frequently when they are at an advanced stage, producing a mass effect and/or hypothalamic. However, the most enigmatic form of granulomatous hypophysitis is idiopathic. Exceptional is the association of this inflammatory lesion with adenomatous neoplastic one. The aim of our report was to make assumptions on the pathogenesis of this unlikely association. Read More>>>>>>

Molecular Beacon-Based Microrna Biosensor for Imaging EPC-Treated Cellular Therapy of Ischemia

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Angiogenesis are basic processes of new blood vessels formation. Vasculogenesis entails the differentiation of mesodermal cells into endothelial precursor cells. When vascular damage is occurred, vessels are able to regenerate via angiogenesis, which is formation of blood vessel from pre-existing blood vessel by the sprouting, splitting, and remodeling of the vascular network.

Isolation of mononuclear cell population from cord blood
Isolation of mononuclear cell population from cord blood

Since the discovery of endothelial precursor cells (EPCs) has been believed that vasculogenesis be able to occur in adult, they have used for the application of cell therapy using putative endothelial cell population for several vascular diseases. With this cell therapy concept several kinds of cellular sources which obtained from adult source were highlighted as stem cell reservoir, including cord blood, peripheral blood, fat, bone marrow, liver, and etc.  Read More>>>>>>>

Obstetric Fistula – An Unceasing Scourge in the Developing World

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Obstetric fistula is a devastating problem known to mankind from time immemorial. It is an abnormal opening into the vagina leading to continuous involuntary leakage of urine and/or faeces following childbirth. The commonest type is vesicovaginal fistula. Other variants include rectovaginal fistula, urethrovaginal fistula, ureterovaginal fistula and vesicouterine fistula.

Obstetric Fistula
Obstetric Fistula

It is a complication of childbirth seen among reproductive-age women who lack access to quality maternity care. It is characterized by urinary and/or faecal incontinence and the resultant shame and social exclusion.While obstetric fistula has virtually disappeared from the developed world, it has remained unremitting in the developing world due to poverty, illiteracy, noxious cultural practices and fragile health systems that have shown minimal improvement over time.  Read More>>>>>>>