autologous progenitor cells transplantation journals
EAM as a New Conditioning Regimen for Lymphoma Patients Undergoing Autologous Progenitor Cell Transplantation
Autologous progenitor cells transplantation (APCT) after a high dose conditioning chemotherapy is now an established treatment modality for many hematological malignancies such as lymphoma.
Clinical results and survival after APCT depend on disease chemo sensitivity at transplant and the efficacy of the conditioning regimen at eradicating the residual tumor cell clone. The impact of the conditioning regimen is a controversial matter and despite efforts to identify high-dose regimens with increasing antitumor activity and acceptable toxicity to normal tissues, there is not yet clear evidence of a superior conditioning platform that should be applied in the setting of recurring lymphoma patients, at least in terms of tumor-eradicating capacity. Read More>>>