necrosis research journals

Effect of Ethanolic Extract of Coconut (Cocos nucifera) on Aspirin-induced Gastric Ulcer in Albino Rats

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Andre Robert introduced the term ‘cytoprotection’ first time. He used this term for protection of experimentally induced gastric ulcer by prostaglandins. But later on, this term is broadly used for protection of gastric mucosal injury except injuries caused by gastric acid inhibition or neutralization.

Desquamation prevalence in stomach ulcer
Desquamation prevalence in stomach ulcer

Despite intensive research of the last few decades, gastro-protection is incompletely understood, and we are still far away from effectively treating Helicobacter pylori -negative ulcers and preventing non-steroidal anti-inflammatory drugs-caused erosions and ulcers in the upper and lower gastrointestinal tract; hence “gastric cytoprotection” research is still relevant. Aspirin, also known as acetylsalicylic acid, is commonly used as an analgesic, antiinflammatory, antipyretic, antiplatelet and antithrombotic drug. Read More>>>>>>>


Identification of Apoptotic Cells by Means of Lectin Histochemistry

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Controlling the number of cells within a tissue is performed by the proliferation and cell death, both involved in the maintenance of the number of cells within a tissue. Consequently, the cell cycle includes both the cell proliferation cycle and programmed cell death (apoptosis).


Morphologically, apoptosis can be visualized microscopically. Some changes can be observed with the light microscope, sometimes using specific staining, and other changes can only be detected by transmission electron microscopy. Unlike necrosis, early changes involving nuclear chromatin condensation around the nuclear perimeter depend on the context, the separation of neighboring cells and the connections to the extracellular matrix.  Read more>>>>>>>>>>>>>>>>>>>