Effects of Preoperative Platelet Count on Blood Loss for Splenectomy with Esophagogastric Devascularization
Hepatitis B cirrhosis is defined as the histological development of regenerative nodules surrounded by fibrous bands due to hepatitis B virus (HBV). It has been estimated 1 million deaths yearly worldwide from complications for liver cirrhosis. Cirrhosis accounts for 90% of portal hypertension.
Hypersplenism and esophagogastric varices are most common clinical manifestations of liver cirrhosis and portal hypertension. Hypersplenism leads to decrease in platelet counts, leukocyte counts and rapidly destruct the blood cells. Severe thrombocytopenia due to hypersplenism significantly increases the risk of spontaneous bleeding and can postpone diagnostic or therapeutic procedures for cirrhosis patients, for instance, liver biopsy, interferon therapy and surgery. Read more>>>>>>>>>>>>>>>>
OMICS Journals 